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The boron neutorn capture therapy (BNCT) status to go into the new era

Zhou Yongmao

Strategic Study of CAE 2012, Volume 14, Issue 8,   Pages 4-13

Abstract: style="text-align: justify;">The paper briefly interprets the obvious progress of the boron neutorn capturetherapy (BNCT) in the new era.boron concentration quantifed detecting, the targeting boron compound composing and the in hospitor neutron

Keywords： neutron capture therapy     clinical trial     tumour recurrence     boron concentration detect     targeting boroncompound     in hospital neutron irradiator    

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Boron neutron capture therapy for glioblastoma of prospects and confused

Zhou Youxin,Sun Ting,Yang Weilian,Du Ziwei

Strategic Study of CAE 2012, Volume 14, Issue 8,   Pages 82-84

Abstract:

Boron neutron capture therapy (BNCT) is a selective radiotherapy of damagecentury in developed countries, but it was limited because of the development of boron carrier and neutron

Keywords： boron neutron capture therapy     glioblastoma multiform     glioma stem cells    

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Boron neutron capture therapy of gliomas and refractory pituitary adenomas: current status and future

Dai Congxin,Yao Yong,Wang Renzhi

Strategic Study of CAE 2012, Volume 14, Issue 8,   Pages 96-99

Abstract:

Clinical study of boron neutron capture therapy (BNCT) for gliomas has

Keywords： boron neutron capture therapy     gliomas     refractory pituitary adenomas    

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Studies on preparation of folate-targeted boron liposomes as potential delivery agents for neutron capture

Wang Zhihui,Qin Linxue,Liu Dong

Strategic Study of CAE 2012, Volume 14, Issue 8,   Pages 78-81

Abstract: liposomes with high encapsulation efficiency is an effective targeted drug delivery agent for boron neutroncapture therapy (BNCT).

Keywords： boron neutron capture therapy     liposomes     folate-targeted     encapsulation efficiency    

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Performance and characteristic of in-hospital neutron irradiator

Li Yiguo,Xia Pu,Peng Dan,Zou Shuyun,Wu Xiaobo,Zhang Jinhua,Zhang Zizhu,Gao Jijin,Wang Liyu,Fu Jinshu,Liu Tong,Zhou Yongmao

Strategic Study of CAE 2012, Volume 14, Issue 8,   Pages 20-22

Abstract:

The design of in hospital neutron irradiator (IHNI) and its systems were

Keywords： in-hospital neutron irradiator(IHNI)     boron neutron capture therapy(BNCT)     inherent safety    

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The physics scheme design for In-Hospital Neutron Irradiator Mark 1 reactor loaded low enrichment fuel

Jiang Xinbiao,Zhang Wenshou,Gao Jijin,Li Yiguo,Zhou Yongmao

Strategic Study of CAE 2009, Volume 11, Issue 11,   Pages 17-21

Abstract:

The core physics properties of 30 kW In-Hospital Neutron Irradiator-Markbeen discovered in the paper and it will provide theoretic basis for reactor engineering design and neutronbeam design for Boron Neutron Capture Therapy in the future.

Keywords： IHNI-1 reactor     boron neutron capture therapy     reactivity    

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Neutron capture therapy clinical development in the world

Zhang Zichu,Jin Congjun,Liu Kai,Zhang Guozhen,Yang Lijun

Strategic Study of CAE 2012, Volume 14, Issue 8,   Pages 100-105

Abstract:

Boron neutron capture therapy (BNCT) method was applied to about one

Keywords： BNCT     GBM     malignant melanoma     recurent head & neck cancer     metastatic liver cancer    

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Experimental study on BPA uptake of glioma cell lines

Yang Lei,Wang Xiao,Sui Li,Kong Fuquan,Hao Xiaojuan,Zheng Jieying,Ma Nanru,Cui Suzhen,Liu Quanwei,Zhao Kui

Strategic Study of CAE 2012, Volume 14, Issue 8,   Pages 85-90

Abstract:

Objective: to evaluate the incorporation of BPA by glioma cell lines, and to observe its relationship with the temperature and the concentration of BPA. Methods: C6, U251 and rat astrocyte cells were incubated in a culture medium, in which 10B concentration was 20, 40, 60, 80, 100 μg/mL for 24 h. Boron concentration in the cells was measured induced couple plasma-atomic emission spectroscopy (ICP-AES). C6 cells were pre-incubated for 24 h with different boron concentrations in growth medium. Then the mediums were changed to boron-free ones, and boron content was assessed after 1, 2, 3 h. Results: The content of the 10B in cells was increasing with the increasing concentration of BPA, and the boron concentration ratios of glioma cells to astrocyte are 2.2. The BPA efflux is slower at the lower temperature. Conclusion: BPA has a selectivity for glioma cells, and the results of the efflux assay confirm the temperature dependence of the BPA transport out of the cells.

Keywords： boron neutron capture therapy     BPA     glioma cell line     ICP AES    

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Optimization design for the epithermal neutron duct of in-hospital neutron irradiator mark 1 reactor

Jiang Xinbiao,Zhu Yangni,Zhao Zhumin,Chen Lixin,Zhou Yongmao

Strategic Study of CAE 2012, Volume 14, Issue 8,   Pages 33-37

Abstract: text-align: justify;">Optimization design for the moderation layer and reflection layer of the epithermal neutronduct at in-hospital neutron irradiator mark 1(IHNI-1) reactor is carried out by using MCNP in this papercompared with Al materials, and two moderation optimization schemes which can obtain intensive epithermal neutronFinally, based on the moderation layer and reflection layer optimization schemes, the neutron and gammaspace distribution of the epithermal neutron beam at exit of this duct are detailed calculated.

Keywords： IHNI-1 reactor     epithermal neutron beam     neutron flux density    

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Dynamic modelling and simulation of a post-combustion CO capture process for coal-fired power plants

Frontiers of Chemical Science and Engineering 2022, Volume 16, Issue 2,   Pages 198-209 doi: 10.1007/s11705-021-2057-7

Abstract: Solvent-based post-combustion capture technologies have great potential for CO2 mitigationComposed by a series of partial differential equations, first-principle post-combustion capture modelsand simplify the chemical and physical process, based on which a universal and hybrid post-combustion captureflue gas flow, and the gas-liquid ratio can be optimized to reduce the reboiler power under a certain capture

Keywords： CO2 capture     post-combustion capture     simulation     dominant factor    

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Reduction potential of the energy penalty for CO capture in CCS

Frontiers in Energy 2023, Volume 17, Issue 3,   Pages 390-399 doi: 10.1007/s11708-023-0864-x

Abstract: CO2 capture and storage (CCS) has been acknowledged as an essential part of a portfolio ofOne of the crucial reasons for this delay lies in the unaffordable penalty caused by CO2 captureFrom the aspects of separation and capture technology innovation, the potential and promising direction

Keywords： CO2 capture and storage (CCS)     CO2 separation     energy penalty    

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Air bearing center cross gap of neutron stress spectrometer sample table support system

Yang LI,Yunxin WU,Hai GONG,Xiaolei FENG

Frontiers of Mechanical Engineering 2016, Volume 11, Issue 4,   Pages 403-411 doi: 10.1007/s11465-016-0405-y

Abstract:

A support system is the main load-bearing component of sample table for neutron stress spectrometerThe neutron stress spectrometer sample table was introduced, and the scheme for air bearing combination

Keywords： neutron stress spectrometer     sample table     support system     air bearing     center cross gap     simulation     experiment    

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How to judge the association of postmenopausal hormone therapy and the risk of breast cancer

Ling XU

Frontiers of Medicine 2010, Volume 4, Issue 3,   Pages 290-293 doi: 10.1007/s11684-010-0093-7

Abstract: The relevance of postmenopausal hormone therapy (HT) for breast cancer risk has been long debated, althoughThese unanswered questions include: whether HT has a positive impact on breast cancer; whether risks of therapy

Keywords： breast cancer     postmenopausal hormone therapy     unopposed estrogen therapy     combined estrogen-progestin therapy    

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Linking renewables and fossil fuels with carbon capture via energy storage for a sustainable energy future

Dawid P. Hanak, Vasilije Manovic

Frontiers of Chemical Science and Engineering 2020, Volume 14, Issue 3,   Pages 453-459 doi: 10.1007/s11705-019-1892-2

Abstract: Renewable energy sources and low-carbon power generation systems with carbon capture and storage (CCS

Keywords： carbon capture     energy storage     renewable energy sources     decarbonisation     fossil fuels    

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Preliminary characterization of radiation fields of IHNI-1 for BNCT

Chen Jun,Li Chunjuan,Song Mingzhe,Li Wei,Yao Shunhe,Diao Lijun,Yao Yanling,Zhang Zizhu,Gao Jijin,Zhang Yifan

Strategic Study of CAE 2012, Volume 14, Issue 8,   Pages 106-112

Abstract:

The characteristic parameters of the neutron radiation fields producedby an in-hospital neutron irradiatior for boron neutron capture therapy(BNCT), such as neutron energyspectra, neutron flux density and neutron absorbed dose rate and their spatial distributions in freeimprove the energy resolution in epithermal energy range and the ability to discriminate different neutronThe preliminary results show that the neutron flux densities of the irradiators achieve the expected

Keywords： in-hospital neutron irradiatior for BNCT     neutron enengy spectrum     neutron flux density     absorbed doserate of neutron and γ ray    

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Title Author Date Type Operation

The boron neutorn capture therapy (BNCT) status to go into the new era

Zhou Yongmao

Journal Article

Boron neutron capture therapy for glioblastoma of prospects and confused

Zhou Youxin,Sun Ting,Yang Weilian,Du Ziwei

Journal Article

Boron neutron capture therapy of gliomas and refractory pituitary adenomas: current status and future

Dai Congxin,Yao Yong,Wang Renzhi

Journal Article

Studies on preparation of folate-targeted boron liposomes as potential delivery agents for neutron capture

Wang Zhihui,Qin Linxue,Liu Dong

Journal Article

Performance and characteristic of in-hospital neutron irradiator

Li Yiguo,Xia Pu,Peng Dan,Zou Shuyun,Wu Xiaobo,Zhang Jinhua,Zhang Zizhu,Gao Jijin,Wang Liyu,Fu Jinshu,Liu Tong,Zhou Yongmao

Journal Article

The physics scheme design for In-Hospital Neutron Irradiator Mark 1 reactor loaded low enrichment fuel

Jiang Xinbiao,Zhang Wenshou,Gao Jijin,Li Yiguo,Zhou Yongmao

Journal Article

Neutron capture therapy clinical development in the world

Zhang Zichu,Jin Congjun,Liu Kai,Zhang Guozhen,Yang Lijun

Journal Article

Experimental study on BPA uptake of glioma cell lines

Yang Lei,Wang Xiao,Sui Li,Kong Fuquan,Hao Xiaojuan,Zheng Jieying,Ma Nanru,Cui Suzhen,Liu Quanwei,Zhao Kui

Journal Article

Optimization design for the epithermal neutron duct of in-hospital neutron irradiator mark 1 reactor

Jiang Xinbiao,Zhu Yangni,Zhao Zhumin,Chen Lixin,Zhou Yongmao

Journal Article

Dynamic modelling and simulation of a post-combustion CO capture process for coal-fired power plants

Journal Article

Reduction potential of the energy penalty for CO capture in CCS

Journal Article

Air bearing center cross gap of neutron stress spectrometer sample table support system

Yang LI,Yunxin WU,Hai GONG,Xiaolei FENG

Journal Article

How to judge the association of postmenopausal hormone therapy and the risk of breast cancer

Ling XU

Journal Article

Linking renewables and fossil fuels with carbon capture via energy storage for a sustainable energy future

Dawid P. Hanak, Vasilije Manovic

Journal Article

Preliminary characterization of radiation fields of IHNI-1 for BNCT

Chen Jun,Li Chunjuan,Song Mingzhe,Li Wei,Yao Shunhe,Diao Lijun,Yao Yanling,Zhang Zizhu,Gao Jijin,Zhang Yifan

Journal Article